The effect of feeding 3'-methyl-4-dimethylaminoazobenzene on tryptophan metabolism of rats.
نویسندگان
چکیده
Liver tryptophan pyrrolase and kynureninase activity decreased when rats were fed the hepatic carcinogen 3'-methyl-4-dimethylaminoazobenzene, whereas li ver kynurenine transaminase activity did not differ significantly from that of the controls. Liver tumors induced by this aminoazo dye had very low kynurenine transaminase activity and no detectable tryptophan pyrrolase or kynureninase activity. None of the enzymes were detectable in the Novikoff hepatoma.
منابع مشابه
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ورودعنوان ژورنال:
- Cancer research
دوره 21 شماره
صفحات -
تاریخ انتشار 1961